The LAC/USC Gynecologic Oncology Division is one of the largest and most active in the country. The objectives of this project is to facilitate the division activities in the areas of cancer screening and outreach; cancer education; and cancer research through the mechanism of grant support for administrative, professional and secretarial personnel. The goals for the current year are to complete the development of a protocol for diagnosis and treatment of the common gynecologic cancers. This will be made available to tumor boards and physicians. The educational and outreach programs will be continued at their present level. Our cancer research projects on hormone receptors in endometrial cancer will be extended to selected neighboring community hospitals. A collaborative study with the Jet Propulsion Laboratory on the analysis of two dimensional maps of tumor proteins is planned.